Below you will find pages that utilize the taxonomy term “History”
Posts
Hypoallergenic Cats Revisited
In the process of a major overhaul of my blogs, the details of which I describe on my personal site, I revisited all of my old posts. I’ve been publishing these little essays online since 2006, and my very first science blogging post was a discussion of the then-new hypoallergenic cats from Allerca:
Specifically, they’re cats that don’t express the gene for the most significant feline allergen protein. They are not clones, nor are they genetically modified in the same way many of our crops are these days, but they’re also not quite “natural.
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75 Years of Molecular Biology
In the November 1943 issue of the journal Genetics, Salvador Luria and Max Delbrück settled a long-running but arcane debate among bacteriologists. The original paper is freely downloadable, and is an amazing document to read today.
There’s a delightful innocence in the simplicity of the experimental design, the lengthy explication of the theory behind the work, and the humbleness of the authors’ conclusions. There is no hint that the paper is describing the dawn of molecular biology, a field that would revolutionize humanity’s relationship with nature in ways that are still unfolding 75 years later.
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Welcome to The Turbid Plaque
In 1915, the director of a veterinary hospital in London was trying to grow viruses in his lab. At the time, researchers had a general idea that viruses were some kind of ultra-small microbes. They caused diseases, but could pass through filters fine enough to remove all known bacteria. Unfortunately, nobody had figured out how to culture them. The veterinary hospital director, a physician named F. W. Twort, decided to use a brute-force approach.
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From Jamaica Ginger to Vicks VapoRub
A new paper in the journal CHEST presents the case of a toddler who went into respiratory distress after receiving a smear of Vicks VapoRub under her nose. To figure out what happened, the researchers replicated the treatment in ferrets, whose respiratory systems are a good model for humans. The results were not exactly consistent with the Vicks “Breathe free” slogan:
[VapoRub] stimulates mucin secretion and [mucociliary transport] in the … inflamed ferret airway.
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Ever Since Fish: Traversing the Change-Time Continuum
Recently, I was talking to a researcher about a particular virus, and he mentioned that it has infected us “since fish.” Yes, fish have a time dimension. In two words, he had communicated reams of information: this virus has infected vertebrates ever since the divergence of the common ancestors of fish and mammals - somewhere around 395 million years ago. That implies that all of the species descended from those ancestors should have their own strains of the virus, which will have co-evolved alongside their host species.