The Turbid Plaque

Life is complicated

Welcome to the second issue of The Filtrate, motto: "All the news that fits through a 0.2µm RSS feed."

This paper describes a new animal model for studying one of the most annoying aspects of dengue fever virus: post-vaccination infection enhancement, in which prior immunity to one strain of the...

"Gee, I should blog about that," says Alan a few times a day. Then the link goes into an immense pile of similar bookmarks, never to be seen on these pages. Let's try something different: a list of papers I've found interesting in the past week, with brief comments about each.

What if we could use...

On a blustery day in mid-December, TWiV co-host Vincent Racaniello and I, along with friend-of-the-show Islam Hussein, visited the picturesque campus of the Tufts University School of Veterinary Medicine in Grafton, MA. Our primary job there was to record an episode of TWiV in front of a live au...

When I was a graduate student at Columbia University, I had the extraordinary privilege of working in the same building as one of the world's greatest medical research libraries. When I saw a reference to a paper I wanted to read, I could usually lay my hands on a copy of it within minutes, no mat...

Since at least 1918, when the "Spanish Flu" swept across the world, leaving a trail of corpses in its wake, Americans have blamed influenza outbreaks on other countries. These days we like to point fingers eastward, invoking images of ancient agricultural practices and chaotic live animal markets...

In the November 1943 issue of the journal Genetics, Salvador Luria and Max Delbrück settled a long-running but arcane debate among bacteriologists. The original paper is freely downloadable, and is an amazing document to read today.

There's a delightful innocence in the simplicity of the exper...